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The Substance

Streaming on Disney+, Hulu.

The Substance poster
Released
September 20, 2024
Runtime
2 hr 21 min
Rated
R
Genre
Drama, Horror, Sci-Fi

Streaming onDisney+#16Hulu#11

Director
Coralie Fargeat
Starring
Demi Moore,Margaret Qualley,Dennis Quaid

A fading celebrity takes a black-market drug: a cell-replicating substance that helps her create a younger, better version of herself.

Scores

80of 100

The average of its 3 scores, each put on a 0 to 100 scale.

Does the dog die? Spoiler-free content warnings for The Substance.

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Box office

US and Canada
$17.6 million
Worldwide
Not reported yet

Totals to date in US dollars, as of November 11, 2026.

If you liked this

Data from Rotten Tomatoes and OMDb API, updated November 11 at 12:43 PM EST. US listings in Rotten Tomatoes' popular order; availability can change. Movie details, available ratings and US/Canada grosses.